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Families, friends, enemies and lovers experience life-changing events in the large upstate New York city of Port Charles, which has a busy hospital, upscale hotel, cozy diner and dangerous waterfront frequented by the criminal underworld.

A young man reflects on a day spent with his estranged mother, in an attempt to understand her enduring trauma and its effect on their relationship.

A mad doctor puts together a new body by using body parts he steals from a mortuary at the hospital where he works.

Jung Ha Yoon is a graduate student who successfully passed the bar exam. However, she is not finished as she wants to be a medical malpractice litigation specialist. She works at a hospital to look to gain experience and there she meets other doctors who work there.

General Hospital: Night Shift is an American prime time serial that first aired on Soapnet for a 13-episode run from July 12, 2007 to October 4, 2007. A spin-off of the ABC Daytime soap opera General Hospital, the show is SOAPnet's first original scripted drama series and follows the nighttime adventures of familiar and new characters around the hospital. As of March 2008, the first season of the series was "SOAPnet's most watched series ever," with ABC Daytime and SOAPnet President Brian Frons noting that Night Shift drew more than 1 million new viewers to the channel during its first season. With its reruns gaining higher ratings than those of General Hospital on SOAPnet, a second season was expected, though Frons noted that the same crew producing two shows had taken its toll.It was announced in May 2008 that Lisa de Cazotte would serve as Executive producer for season two, joined by Head writer Sri Rao. The 14 new episodes of Night Shift began taping in high-definition in June 2008, with the series airing Tuesdays at 11 p.m. and premiering on July 22, 2008. SOAPnet said the second season "will feature new and returning characters as well as the return of 'legacy' characters from GH. In addition, the continuity between story lines on Night Shift and GH will match." The second season finished its run on October 21, 2008.

Dr. Bock, the chief of medicine at a Manhattan hospital, is suicidal after the collapse of his personal life. When an intern is found dead in a hospital bed, it appears to Bock to be a case of unforgivable malpractice. Hours later, another doctor, who happens to be responsible for another case of malpractice, is found dead. Despondent, Bock finds himself drawn to Barbara, the daughter of a comatose missionary.

舊聖利奧波德醫院周遭有許多靈異的傳聞，這裡的居民深信這間醫院受到了詛咒，而不敢靠近。一天，一位女大生為了研究論文來到這間醫院，卻也在不久後就消失不見。一群不信邪的辣妹參加了電視台的靈異節目，要到這間醫院住上一晚，但她們發現的不是鬼，而是躲藏在醫院的變態殺人魔們。前所未有的可怕殺戮即將襲來，究竟誰能活著走出醫院大門？

The killer class is back in session—sort of. Relive every moment through the eyes of the top two students: Nagisa and Karma!